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Nitric oxide differentially affects ERK and Akt in type 1 and type 2 diabetic rats

BACKGROUND: We have shown that nitric oxide (NO) is more effective at inhibiting neointimal hyperplasia in type 2 diabetic rats than in nondiabetic rats, but is not effective in type 1 diabetic rats. Insulin signaling is mediated by the ERK and Akt pathways, and thus we hypothesized that NO differen...

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Hlavní autoři: Rodriguez, Monica P., Emond, Zachary M., Varu, Vinit N., Ahanchi, Sadaf S., Martinez, Janet, Kibbe, Melina R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3964777/
https://ncbi.nlm.nih.gov/pubmed/23608617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2013.02.055
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