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Engineered Biomaterials Control Differentiation and Proliferation of Human-Embryonic-Stem-Cell-Derived Cardiomyocytes via Timed Notch Activation

For cell-based treatments of myocardial infarction, a better understanding of key developmental signaling pathways and more robust techniques for producing cardiomyocytes are required. Manipulation of Notch signaling has promise as it plays an important role during cardiovascular development, but pr...

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Detalhes bibliográficos
Main Authors: Tung, Jason C., Paige, Sharon L., Ratner, Buddy D., Murry, Charles E., Giachelli, Cecilia M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3964284/
https://ncbi.nlm.nih.gov/pubmed/24672751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.01.011
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