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Among 45 variants in 11 genes, HDM2 promoter polymorphisms emerge as new candidate biomarker associated with radiation toxicity

Due to individual variations in radiosensitivity, biomarkers are needed to tailor radiation treatment to cancer patients. Since single nucleotide polymorphisms (SNPs) are frequent in human, we hypothesized that SNPs in genes that mitigate the radiation response are associated with radiotoxicity, in...

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Detalhes bibliográficos
Main Authors: Alsbeih, Ghazi, El-Sebaie, Medhat, Al-Rajhi, Nasser, Al-Harbi, Najla, Al-Hadyan, Khaled, Al-Qahtani, Sara, Alsubael, Mohammad, Al-Shabanah, Mohammad, Moftah, Belal
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3964253/
https://ncbi.nlm.nih.gov/pubmed/28324443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13205-013-0135-3
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