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Graph-based sampling for approximating global helical topologies of RNA

A current challenge in RNA structure prediction is the description of global helical arrangements compatible with a given secondary structure. Here we address this problem by developing a hierarchical graph sampling/data mining approach to reduce conformational space and accelerate global sampling o...

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Detalhes bibliográficos
Main Authors: Kim, Namhee, Laing, Christian, Elmetwaly, Shereef, Jung, Segun, Curuksu, Jeremy, Schlick, Tamar
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3964109/
https://ncbi.nlm.nih.gov/pubmed/24591615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1318893111
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