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Stalled transcription complexes promote DNA repair at a distance
Transcription-coupled nucleotide excision repair (TCR) accelerates the removal of noncoding lesions from the template strand of active genes, and hence contributes to genome-wide variations in mutation frequency. Current models for TCR suppose that a lesion must cause RNA polymerase (RNAP) to stall...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3964087/ https://ncbi.nlm.nih.gov/pubmed/24554077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1322350111 |
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