Interleukin-27 acts on dendritic cells to suppress the T-cell response and autoimmunity by inducing the expression of ENTPD1 (CD39)

Dendritic cells (DCs) control the balance between effector and regulatory T cells in vivo. Hence, the study of DCs might identify mechanisms of disease pathogenesis and guide new therapeutic approaches for immune-mediated disorders. We found that IL-27 signaling in murine DCs limits the generation o...

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Detalhes bibliográficos
Main Authors: Mascanfroni, Ivan D., Yeste, Ada, Vieira, Silvio M., Burns, Evan J., Patel, Bonny, Sloma, Ido, Wu, Yan, Mayo, Lior, Ben-Hamo, Rotem, Efroni, Sol, Kuchroo, Vijay K., Robson, Simon C., Quintana, Francisco J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3964005/
https://ncbi.nlm.nih.gov/pubmed/23995234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2695
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