The effect of cyclosporin-A on peri-operative myocardial injury in adult patients undergoing coronary artery bypass graft surgery: a randomised controlled clinical trial

OBJECTIVE: Cyclosporin-A (CsA) has been reported to reduce myocardial infarct size in both the experimental and clinical settings. This protective effect is dependent on its ability to prevent the opening of the mitochondrial permeability transition pore, a critical determinant of cell death in the...

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Detalhes bibliográficos
Main Authors: Hausenloy, DJ, Kunst, G, Boston-Griffiths, E, Kolvekar, S, Chaubey, S, John, L, Desai, J, Yellon, DM
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2014
Assuntos:
Cardiovascular Surgery
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963550/
https://ncbi.nlm.nih.gov/pubmed/24488610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/heartjnl-2013-304845
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