The effect of cyclosporin-A on peri-operative myocardial injury in adult patients undergoing coronary artery bypass graft surgery: a randomised controlled clinical trial

OBJECTIVE: Cyclosporin-A (CsA) has been reported to reduce myocardial infarct size in both the experimental and clinical settings. This protective effect is dependent on its ability to prevent the opening of the mitochondrial permeability transition pore, a critical determinant of cell death in the...

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Autori principali: Hausenloy, DJ, Kunst, G, Boston-Griffiths, E, Kolvekar, S, Chaubey, S, John, L, Desai, J, Yellon, DM
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Publishing Group 2014
Soggetti:
Cardiovascular Surgery
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963550/
https://ncbi.nlm.nih.gov/pubmed/24488610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/heartjnl-2013-304845
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