Development of Purine-Derived (18)F-Labeled Pro-drug Tracers for Imaging of MRP1 Activity with PET

[Image: see text] Multidrug resistance-associated protein 1 (MRP1) is a drug efflux transporter that has been implicated in the pathology of several neurological diseases and is associated with development of multidrug resistance. To enable measurement of MRP1 function in the living brain, a series...

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Bibliographische Detailangaben
Hauptverfasser: Galante, Eva, Okamura, Toshimitsu, Sander, Kerstin, Kikuchi, Tatsuya, Okada, Maki, Zhang, Ming-Rong, Robson, Mathew, Badar, Adam, Lythgoe, Mark, Koepp, Matthias, Årstad, Erik
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2014
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963453/
https://ncbi.nlm.nih.gov/pubmed/24456310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm401764a
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