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Radial Symmetry in a Chimaeric Glutamate Receptor Pore

Ionotropic glutamate receptors comprise two conformationally different A/C and B/D subunit pairs. Closed channels exhibit 4-fold radial symmetry in the transmembrane domain (TMD) but transition to 2-fold dimer-of-dimers symmetry for extracellular ligand binding and N-terminal domains. Here, to evalu...

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書目詳細資料
Main Authors: Wilding, Timothy J, Lopez, Melany N., Huettner, James E.
格式: Artigo
語言:Inglês
出版: 2014
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962659/
https://ncbi.nlm.nih.gov/pubmed/24561802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4349
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