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Role of aromatase in sex-specific cerebrovascular endothelial function in mice

Stroke risk and outcome are strongly modified by estrogen. In addition to ovaries, estrogen is produced locally in peripheral tissue by the enzyme aromatase, and extragonadal synthesis becomes the major source of estrogen after menopause. Aromatase gene deletion in female mice exacerbates ischemic b...

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Autors principals: Zuloaga, Kristen L., Davis, Catherine M., Zhang, Wenri, Alkayed, Nabil J.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962636/
https://ncbi.nlm.nih.gov/pubmed/24508640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00698.2013
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