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Role of aromatase in sex-specific cerebrovascular endothelial function in mice

Stroke risk and outcome are strongly modified by estrogen. In addition to ovaries, estrogen is produced locally in peripheral tissue by the enzyme aromatase, and extragonadal synthesis becomes the major source of estrogen after menopause. Aromatase gene deletion in female mice exacerbates ischemic b...

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Detalhes bibliográficos
Main Authors: Zuloaga, Kristen L., Davis, Catherine M., Zhang, Wenri, Alkayed, Nabil J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962636/
https://ncbi.nlm.nih.gov/pubmed/24508640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00698.2013
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