Enhanced large conductance K(+) channel activity contributes to the impaired myogenic response in the cerebral vasculature of Fawn Hooded Hypertensive rats

Recent studies have indicated that the myogenic response (MR) in cerebral arteries is impaired in Fawn Hooded Hypertensive (FHH) rats and that transfer of a 2.4 megabase pair region of chromosome 1 (RNO1) containing 15 genes from the Brown Norway rat into the FHH genetic background restores MR in a...

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Hlavní autoři: Pabbidi, Mallikarjuna R., Mazur, Olga, Fan, Fan, Farley, Jerry M., Gebremedhin, Debebe, Harder, David R., Roman, Richard J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2014
Témata:
Vascular Biology and Microcirculation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962634/
https://ncbi.nlm.nih.gov/pubmed/24464756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00636.2013
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