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High-density array analysis of DNA methylation in Tamoxifen-resistant breast cancer cell lines
Roughly two-thirds of all breast cancers are ERα-positive and can be treated with the antiestrogen, Tamoxifen, however resistance occurs in 33% of women who take the drug for more than 5 y. Aberrant DNA methylation, an epigenetic mechanism that alters gene expression in cancer, is thought to play a...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Landes Bioscience
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3962540/ https://ncbi.nlm.nih.gov/pubmed/24225485 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.27111 |
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