Searching for Novel Cdk5 Substrates in Brain by Comparative Phosphoproteomics of Wild Type and Cdk5(−/−) Mice

Protein phosphorylation is the most common post-translational modification that regulates several pivotal functions in cells. Cyclin-dependent kinase 5 (Cdk5) is a proline-directed serine/threonine kinase which is mostly active in the nervous system. It regulates several biological processes such as...

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Bibliographic Details
Main Authors: Contreras-Vallejos, Erick, Utreras, Elías, Bórquez, Daniel A., Prochazkova, Michaela, Terse, Anita, Jaffe, Howard, Toledo, Andrea, Arruti, Cristina, Pant, Harish C., Kulkarni, Ashok B., González-Billault, Christian
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962345/
https://ncbi.nlm.nih.gov/pubmed/24658276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090363
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