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Computational Enzyme Design: Advances, hurdles and possible ways forward

This mini review addresses recent developments in computational enzyme design. Successful protocols as well as known issues and limitations are discussed from an energetic perspective. It will be argued that improved results can be obtained by including a dynamic treatment in the design protocol. Fi...

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Detalhes bibliográficos
Autor principal: Linder, Mats
Formato: Artigo
Idioma:Inglês
Publicado em: Research Network of Computational and Structural Biotechnology (RNCSB) Organization 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962231/
https://ncbi.nlm.nih.gov/pubmed/24688650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5936/csbj.201209009
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