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Eltrombopag restores trilineage hematopoiesis in refractory severe aplastic anemia that can be sustained on discontinuation of drug

About a quarter of patients with severe aplastic anemia remain pancytopenic despite immunosuppressive therapy. We have previously demonstrated that eltrombopag has efficacy in this setting with 44% (11/25) of patients having clinically significant hematologic responses. We now report safety and effi...

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Autores principales: Desmond, Ronan, Townsley, Danielle M., Dumitriu, Bogdan, Olnes, Matthew J., Scheinberg, Phillip, Bevans, Margaret, Parikh, Ankur R., Broder, Kinneret, Calvo, Katherine R., Wu, Colin O., Young, Neal S., Dunbar, Cynthia E.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962161/
https://ncbi.nlm.nih.gov/pubmed/24345753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-10-534743
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