Rel-deficient T cells exhibit defects in production of interleukin 3 and granulocyte-macrophage colony-stimulating factor.

The c-rel protooncogene encodes a subunit of the NF-kappa B-like family of transcription factors. Mice lacking Rel are defective in mitogenic activation of B and T lymphocytes and display impaired humoral immunity. In an attempt to identify changes in gene expression that accompany the T-cell stimul...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Gerondakis, S, Strasser, A, Metcalf, D, Grigoriadis, G, Scheerlinck, J Y, Grumont, R J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39621/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8622948/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.8.3405
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