ISOFLURANE-INDUCED NEUROAPOPTOSIS IN THE NEONATAL RHESUS MACAQUE BRAIN

BACKGROUND: Brief isoflurane anesthesia induces neuroapoptosis in the developing rodent brain, but susceptibility of nonhuman primates to the apoptogenic action of isoflurane has not been studied. Therefore, we exposed postnatal day 6 (P6) rhesus macaques to a surgical plane of isoflurane anesthesia...

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Main Authors: Brambrink, Ansgar M., Evers, Alex S., Avidan, Michael S., Farber, Nuri B., Smith, Derek J., Zhang, Xuezhao, Dissen, Gregory A., Creeley, Catherine E., Olney, John W.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962067/
https://ncbi.nlm.nih.gov/pubmed/20234312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e3181d049cd
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