Intrathecal carbenoxolone inhibits neuropathic pain and spinal wide-dynamic range neuronal activity in rats after an L5 spinal nerve injury

Spinal glial gap junctions may play an important role in dorsal horn neuronal sensitization and neuropathic pain. In rats after an L5 spinal nerve ligation (SNL), we examined the effects of intrathecal injection of carbenoxolone (CBX), a gap junction decoupler, on neuropathic pain manifestations and...

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Detalhes bibliográficos
Main Authors: Xu, Qian, Cheong, Yong-Kwan, Yang, Fei, Tiwari, Vinod, Li, Jinheng, Liu, Jian, Raja, Srinivasa N., Li, Weiyan, Guan, Yun
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962020/
https://ncbi.nlm.nih.gov/pubmed/24486838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2014.01.042
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