Intrathecal carbenoxolone inhibits neuropathic pain and spinal wide-dynamic range neuronal activity in rats after an L5 spinal nerve injury

Spinal glial gap junctions may play an important role in dorsal horn neuronal sensitization and neuropathic pain. In rats after an L5 spinal nerve ligation (SNL), we examined the effects of intrathecal injection of carbenoxolone (CBX), a gap junction decoupler, on neuropathic pain manifestations and...

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Autors principals: Xu, Qian, Cheong, Yong-Kwan, Yang, Fei, Tiwari, Vinod, Li, Jinheng, Liu, Jian, Raja, Srinivasa N., Li, Weiyan, Guan, Yun
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962020/
https://ncbi.nlm.nih.gov/pubmed/24486838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2014.01.042
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