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Sustained High Protein-tyrosine Phosphatase 1B Activity in the Sperm of Obese Males Impairs the Sperm Acrosome Reaction

Evidence of a causal link between male obesity and subfertility or infertility has been demonstrated previously. However, the mechanism underlying this link is incompletely understood. Here, we report that sustained high protein-tyrosine phosphatase 1B (PTP1B) activity in sperm of obese donors plays...

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Detalhes bibliográficos
Main Authors: Shi, Lei, Zhang, Qipeng, Xu, Binqiang, Jiang, Xiaohong, Dai, Yutian, Zhang, Chen-Yu, Zen, Ke
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961668/
https://ncbi.nlm.nih.gov/pubmed/24519936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.517466
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