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CvfA Protein and Polynucleotide Phosphorylase Act in an Opposing Manner to Regulate Staphylococcus aureus Virulence

We previously identified CvfA (SA1129) as a Staphylococcus aureus virulence factor using a silkworm infection model. S. aureus cvfA-deleted mutants exhibit decreased expression of the agr locus encoding a positive regulator of hemolysin genes and decreased hemolysin production. CvfA protein hydrolyz...

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Bibliografske podrobnosti
Main Authors: Numata, Shunsuke, Nagata, Makiko, Mao, Han, Sekimizu, Kazuhisa, Kaito, Chikara
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961667/
https://ncbi.nlm.nih.gov/pubmed/24492613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.554329
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