Targeting γ-Herpesvirus 68 Bcl-2-mediated Down-regulation of Autophagy

γ-herpesviruses (γHVs) are common human pathogens that encode homologs of the anti-apoptotic cellular Bcl-2 proteins, which are critical to viral reactivation and oncogenic transformation. The murine γHV68 provides a tractable in vivo model for understanding general features of these important human...

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Bibliographic Details
Main Authors: Su, Minfei, Mei, Yang, Sanishvili, Ruslan, Levine, Beth, Colbert, Christopher L., Sinha, Sangita
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2014
Subjects:
Protein Structure and Folding
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961636/
https://ncbi.nlm.nih.gov/pubmed/24443581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.515361
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