Trial Watch: Immunostimulatory monoclonal antibodies in cancer therapy

Immunostimulatory monoclonal antibodies (mAbs) exert antineoplastic effects by eliciting a novel or reinstating a pre-existing antitumor immune response. Most often, immunostimulatory mAbs activate T lymphocytes or natural killer (NK) cells by inhibiting immunosuppressive receptors, such as cytotoxi...

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Autores principales: Aranda, Fernando, Vacchelli, Erika, Eggermont, Alexander, Galon, Jerome, Fridman, Wolf Hervé, Zitvogel, Laurence, Kroemer, Guido, Galluzzi, Lorenzo
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961485/
https://ncbi.nlm.nih.gov/pubmed/24701370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.27297
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