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Antioxidants Impair Anti-Tumoral Effects of Vorinostat, but Not Anti-Neoplastic Effects of Vorinostat and Caspase-8 Downregulation

We have recently demonstrated that histone deacetylase inhibitor, Vorinostat, applied as a single therapy or in combination with caspase-8 downregulation exhibits high anti-tumoral activity on endometrial carcinoma cell lines. In the present study, we have assessed the signalling processes underlyin...

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Detalhes bibliográficos
Main Authors: Bergadà, Laura, Yeramian, Andree, Sorolla, Annabel, Matias-Guiu, Xavier, Dolcet, Xavier
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961419/
https://ncbi.nlm.nih.gov/pubmed/24651472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092764
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