The Role of Host and Microbial Factors in the Pathogenesis of Pneumococcal Bacteraemia Arising from a Single Bacterial Cell Bottleneck

The pathogenesis of bacteraemia after challenge with one million pneumococci of three isogenic variants was investigated. Sequential analyses of blood samples indicated that most episodes of bacteraemia were monoclonal events providing compelling evidence for a single bacterial cell bottleneck at th...

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Główni autorzy: Gerlini, Alice, Colomba, Leonarda, Furi, Leonardo, Braccini, Tiziana, Manso, Ana Sousa, Pammolli, Andrea, Wang, Bo, Vivi, Antonio, Tassini, Maria, van Rooijen, Nico, Pozzi, Gianni, Ricci, Susanna, Andrew, Peter W., Koedel, Uwe, Moxon, E. Richard, Oggioni, Marco R.
Format: Artigo
Język:Inglês
Wydane: Public Library of Science 2014
Hasła przedmiotowe:
Research Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961388/
https://ncbi.nlm.nih.gov/pubmed/24651834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004026
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