The Role of Host and Microbial Factors in the Pathogenesis of Pneumococcal Bacteraemia Arising from a Single Bacterial Cell Bottleneck

The pathogenesis of bacteraemia after challenge with one million pneumococci of three isogenic variants was investigated. Sequential analyses of blood samples indicated that most episodes of bacteraemia were monoclonal events providing compelling evidence for a single bacterial cell bottleneck at th...

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Main Authors: Gerlini, Alice, Colomba, Leonarda, Furi, Leonardo, Braccini, Tiziana, Manso, Ana Sousa, Pammolli, Andrea, Wang, Bo, Vivi, Antonio, Tassini, Maria, van Rooijen, Nico, Pozzi, Gianni, Ricci, Susanna, Andrew, Peter W., Koedel, Uwe, Moxon, E. Richard, Oggioni, Marco R.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961388/
https://ncbi.nlm.nih.gov/pubmed/24651834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004026
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