The Role of Host and Microbial Factors in the Pathogenesis of Pneumococcal Bacteraemia Arising from a Single Bacterial Cell Bottleneck

The pathogenesis of bacteraemia after challenge with one million pneumococci of three isogenic variants was investigated. Sequential analyses of blood samples indicated that most episodes of bacteraemia were monoclonal events providing compelling evidence for a single bacterial cell bottleneck at th...

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Autors principals: Gerlini, Alice, Colomba, Leonarda, Furi, Leonardo, Braccini, Tiziana, Manso, Ana Sousa, Pammolli, Andrea, Wang, Bo, Vivi, Antonio, Tassini, Maria, van Rooijen, Nico, Pozzi, Gianni, Ricci, Susanna, Andrew, Peter W., Koedel, Uwe, Moxon, E. Richard, Oggioni, Marco R.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961388/
https://ncbi.nlm.nih.gov/pubmed/24651834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004026
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