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Fluorodeoxyglucose uptake in laryngeal carcinoma is associated with the expression of glucose transporter-1 and hypoxia-inducible-factor-1α and the phosphoinositide 3-kinase/protein kinase B pathway

High fluorodeoxyglucose (FDG) uptake by human carcinomas, including head and neck cancers, is associated with a poor prognosis. Glucose transporter-1 (Glut-1) is believed to be an intrinsic marker of hypoxia in malignant tumors. The expression of hypoxia-inducible factor-1α (HIF-1α) and correlated t...

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Autors principals: ZHAO, KUI, YANG, SHU-YE, ZHOU, SHUI-HONG, DONG, MENG JIE, BAO, YANG-YANG, YAO, HONG-TIAN
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961369/
https://ncbi.nlm.nih.gov/pubmed/24944654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2014.1877
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