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Identification of OmpA, a Coxiella burnetii Protein Involved in Host Cell Invasion, by Multi-Phenotypic High-Content Screening

Coxiella burnetii is the agent of the emerging zoonosis Q fever. This pathogen invades phagocytic and non-phagocytic cells and uses a Dot/Icm secretion system to co-opt the endocytic pathway for the biogenesis of an acidic parasitophorous vacuole where Coxiella replicates in large numbers. The study...

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Autors principals: Martinez, Eric, Cantet, Franck, Fava, Laura, Norville, Isobel, Bonazzi, Matteo
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961360/
https://ncbi.nlm.nih.gov/pubmed/24651569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004013
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