The Ectodomain of TLR3 Receptor Is Required for Its Plasma Membrane Translocation

Toll-like receptor 3 (TLR3) is a dsRNA sensing receptor that is localized in the cellular compartments but also at the plasma membrane. Overexpression of UNC93B1 promoted localization of TLR3, but not other nucleic acid sensing TLRs, to the plasma membrane. Here we show that UNC93B1 itself is locali...

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Detaylı Bibliyografya
Asıl Yazarlar: Pohar, Jelka, Pirher, Nina, Benčina, Mojca, Manček-Keber, Mateja, Jerala, Roman
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2014
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961339/
https://ncbi.nlm.nih.gov/pubmed/24651829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092391
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