Dual-Layered Nanogel-Coated Hollow Lipid/Polypeptide Conjugate Assemblies for Potential pH-Triggered Intracellular Drug Release

To achieve effective intracellular anticancer drug delivery, the polymeric vesicles supplemented with the pH-responsive outlayered gels as a delivery system of doxorubicin (DOX) were developed from self-assembly of the lipid/polypeptide adduct, distearin grafted poly(γ-glutamic acid) (poly(γ-GA)), f...

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Main Authors: Chiang, Wen-Hsuan, Huang, Wen-Chia, Shen, Ming-Yin, Wang, Che-Hsu, Huang, Yi-Fong, Lin, Sung-Chyr, Chern, Chorng-Shyan, Chiu, Hsin-Cheng
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961315/
https://ncbi.nlm.nih.gov/pubmed/24651156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092268
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