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A Physiologically Based Model of Orexinergic Stabilization of Sleep and Wake

The orexinergic neurons of the lateral hypothalamus (Orx) are essential for regulating sleep-wake dynamics, and their loss causes narcolepsy, a disorder characterized by severe instability of sleep and wake states. However, the mechanisms through which Orx stabilize sleep and wake are not well under...

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Detalhes bibliográficos
Main Authors: Fulcher, Ben D., Phillips, Andrew J. K., Postnova, Svetlana, Robinson, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961294/
https://ncbi.nlm.nih.gov/pubmed/24651580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0091982
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