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L-Arginine Stimulates Fibroblast Proliferation through the GPRC6A-ERK1/2 and PI3K/Akt Pathway

l-Arginine is considered a conditionally essential amino acid and has been shown to enhance wound healing. However, the molecular mechanisms through which arginine stimulates cutaneous wound repair remain unknown. Here, we evaluated the effects of arginine supplementation on fibroblast proliferation...

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Main Authors: Fujiwara, Takashi, Kanazawa, Shigeyuki, Ichibori, Ryoko, Tanigawa, Tomoko, Magome, Takuya, Shingaki, Kenta, Miyata, Shingo, Tohyama, Masaya, Hosokawa, Ko
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961283/
https://ncbi.nlm.nih.gov/pubmed/24651445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092168
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