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Investigation of the Chromosome Regions with Significant Affinity for the Nuclear Envelope in Fruit Fly – A Model Based Approach

Three dimensional nuclear architecture is important for genome function, but is still poorly understood. In particular, little is known about the role of the “boundary conditions” – points of attachment between chromosomes and the nuclear envelope. We describe a method for modeling the 3D organizati...

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Autors principals: Kinney, Nicholas Allen, Sharakhov, Igor V., Onufriev, Alexey V.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961273/
https://ncbi.nlm.nih.gov/pubmed/24651400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0091943
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