DUF1220 Dosage Is Linearly Associated with Increasing Severity of the Three Primary Symptoms of Autism

One of the three most frequently documented copy number variations associated with autism spectrum disorder (ASD) is a 1q21.1 duplication that encompasses sequences encoding DUF1220 protein domains, the dosage of which we previously implicated in increased human brain size. Further, individuals with...

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Bibliographic Details
Main Authors: Davis, Jonathan M., Searles, Veronica B., Anderson, Nathan, Keeney, Jonathon, Dumas, Laura, Sikela, James M.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961203/
https://ncbi.nlm.nih.gov/pubmed/24651471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004241
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