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Increased Expression of Chitinase 3-Like 1 in Aorta of Patients with Atherosclerosis and Suppression of Atherosclerosis in Apolipoprotein E-Knockout Mice by Chitinase 3-Like 1 Gene Silencing

Introduction. The purpose of this study was to investigate the changes of chitinase 3-like 1 (CHI3L1) in the aorta of patients with coronary atherosclerosis and to determine whether inhibition of CHI3L1 by lentivirus-mediated RNA interference could stabilize atherosclerotic plaques in apolipoprotein...

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Main Authors: Gong, Zushun, Xing, Shanshan, Zheng, Fei, Xing, Qichong
格式: Artigo
語言:Inglês
出版: Hindawi Publishing Corporation 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960764/
https://ncbi.nlm.nih.gov/pubmed/24729664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/905463
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