A carregar...

Aberrant apoptotic machinery confers melanoma dual resistance to BRAF(V600E) inhibitor and immune effector cells: immunosensitization by a histone deacetylase inhibitor

BRAF(V600E)-inhibitors (BRAFi; e.g., vemurafenib) and modern immune-based therapies such as PD-1/PD-L1 and CTLA-4 checkpoints blockade and adoptive cell transfer (ACT) have significantly improved the care of melanoma patients. Having these two effective (BRAFi and immunotherapy) therapies raises the...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Jazirehi, Ali R, Nazarian, Ramin, Torres-Collado, Antoni Xavier, Economou, James S
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960761/
https://ncbi.nlm.nih.gov/pubmed/24660121
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!