Elevated serum CXCL16 is an independent predictor of poor survival in ovarian cancer and may reflect pro-metastatic ADAM protease activity

BACKGROUND: In certain cancers, expression of CXCL16 and its receptor CXCR6 associate with lymphocyte infiltration, possibly aiding anti-tumour immune response. In other cancers, CXCL16 and CXCR6 associate with pro-metastatic activity. In the current study, we aimed to characterise the role of CXCL1...

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Detalhes bibliográficos
Main Authors: Gooden, M J M, Wiersma, V R, Boerma, A, Leffers, N, Boezen, H M, ten Hoor, K A, Hollema, H, Walenkamp, A M E, Daemen, T, Nijman, H W, Bremer, E
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960624/
https://ncbi.nlm.nih.gov/pubmed/24518602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.55
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