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TLR4KO mice are protected from endothelial overactivation in the absence of Kupffer cells after total hepatic ischemia/reperfusion
Kupffer cells (KC) have been shown to be critical mediators of I/R injury in the murine liver. Utilizing liposomal clodronate (LC) administration, we have shown that KC are protective in models of total hepatic ischemia with bowel congestion. Here, we investigate the role of TLR4 in the damage that...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3960597/ https://ncbi.nlm.nih.gov/pubmed/21563297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/lt.22333 |
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