Enhanced self-administration of the CB(1) receptor agonist WIN55,212-2 in olfactory bulbectomized rats: evaluation of possible serotonergic and dopaminergic underlying mechanisms

Depression has been associated with drug consumption, including heavy or problematic cannabis use. According to an animal model of depression and substance use disorder comorbidity, we combined the olfactory bulbectomy (OBX) model of depression with intravenous drug self-administration procedure to...

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Detalhes bibliográficos
Main Authors: Amchova, Petra, Kucerova, Jana, Giugliano, Valentina, Babinska, Zuzana, Zanda, Mary T., Scherma, Maria, Dusek, Ladislav, Fadda, Paola, Micale, Vincenzo, Sulcova, Alexandra, Fratta, Walter, Fattore, Liana
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960502/
https://ncbi.nlm.nih.gov/pubmed/24688470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2014.00044
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