Platelet-rich plasma induces annulus fibrosus cell proliferation and matrix production

PURPOSE: Platelet-rich plasma (PRP) contains growth factors and creates a 3D structure upon clotting; PRP or platelet lysate (PL) might be considered for annulus fibrosus (AF) repair. METHODS: Bovine AF cells were cultured with 25 % PRP, 50 % PRP, 25 % PL, 50 % PL, or 10 % FBS. After 2 and 4 days, D...

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Bibliographic Details
Main Authors: Pirvu, T. N., Schroeder, J. E., Peroglio, M., Verrier, S., Kaplan, L., Richards, R. G., Alini, M., Grad, S.
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2014
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960410/
https://ncbi.nlm.nih.gov/pubmed/24469887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00586-014-3198-x
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