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Expression of chimeric receptor CD4ζ by natural killer cells derived from human pluripotent stem cells improves in vitro activity but does not enhance suppression of HIV infection in vivo

Cell-based immunotherapy has been gaining interest as an improved means to treat HIV/AIDS. Human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) could become a potential resource. Our previous studies have shown hESC and iPSC-derived natural killer (NK) cells can inhibit HIV-...

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Detalhes bibliográficos
Main Authors: Ni, Zhenya, Knorr, David A., Bendzick, Laura, Allred, Jeremy, Kaufman, Dan S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960346/
https://ncbi.nlm.nih.gov/pubmed/24307574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1611
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