FOXP3 over-expression inhibits melanoma tumorigenesis via effects on proliferation and apoptosis.

The Forkhead box P3 (FOXP3) transcription factor is the key driver of regulatory T cell (Treg cells) differentiation and immunosuppressive function. In addition, FOXP3 has been reported to be expressed in many tumors, including melanoma. However, its role in tumorigenesis is conficting, with both tu...

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Detalhes bibliográficos
Main Authors: Tan, BeeShin, Anaka, Matthew, Deb, Siddhartha, Freyer, Claudia, Ebert, Lisa M., Chueh, Anderly C., Al-Obaidi, Sheren, Behren, Andreas, Jayachandran, Aparna, Cebon, Jonathan, Chen, Weisan, Mariadason, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2013
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960207/
https://ncbi.nlm.nih.gov/pubmed/24406338
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