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Deciphering intrafamilial phenotypic variability by exome sequencing in a Bardet–Biedl family

Bardet–Biedl syndrome (BBS) is a model ciliopathy characterized by a wide range of clinical variability. The heterogeneity of this condition is reflected in the number of underlying gene defects and the epistatic interactions between the proteins encoded. BBS is generally inherited in an autosomal r...

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Dettagli Bibliografici
Autori principali: González-del Pozo, María, Méndez-Vidal, Cristina, Santoyo-Lopez, Javier, Vela-Boza, Alicia, Bravo-Gil, Nereida, Rueda, Antonio, García-Alonso, Luz, Vázquez-Marouschek, Carmen, Dopazo, Joaquín, Borrego, Salud, Antiñolo, Guillermo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wiley Periodicals, Inc. 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960054/
https://ncbi.nlm.nih.gov/pubmed/24689075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.50
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