Cytochrome P4503A activity affects the gender difference in the development of steroid-induced osteonecrosis in rabbits

The aim of this study was to investigate cytochrome P4503A activity and its correlation with the development of osternecrosis (ON) among male and female steroid-treated rabbits. Forty adult rabbits (male, n = 20; female, n = 20) were injected once with 20 mg/kg of methylprednisolone intramuscularly....

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Bibliographic Details
Main Authors: Ikemura, Satoshi, Yamamoto, Takuaki, Motomura, Goro, Yamaguchi, Ryosuke, Zhao, Garida, Iwasaki, Kenyu, Iwamoto, Yukihide
Format: Artigo
Language:Inglês
Published: Backwell Publishing Ltd 2014
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960042/
https://ncbi.nlm.nih.gov/pubmed/24673874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/iep.12060
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