Expression of alternative oxidase in Drosophila ameliorates diverse phenotypes due to cytochrome oxidase deficiency

Mitochondrial dysfunction is a significant factor in human disease, ranging from systemic disorders of childhood to cardiomyopathy, ischaemia and neurodegeneration. Cytochrome oxidase, the terminal enzyme of the mitochondrial respiratory chain, is a frequent target. Lower eukaryotes possess alternat...

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Bibliografische gegevens
Hoofdauteurs: Kemppainen, Kia K., Rinne, Juho, Sriram, Ashwin, Lakanmaa, Matti, Zeb, Akbar, Tuomela, Tea, Popplestone, Anna, Singh, Satpal, Sanz, Alberto, Rustin, Pierre, Jacobs, Howard T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3959817/
https://ncbi.nlm.nih.gov/pubmed/24293544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt601
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