RANK- and c-Met-mediated signal network promotes prostate cancer metastatic colonization

Prostate cancer (PCa) metastasis to bone is lethal and there is no adequate animal model for studying the mechanisms underlying the metastatic process. Here, we report that receptor activator of NF-κB ligand (RANKL) expressed by PCa cells consistently induced colonization or metastasis to bone in an...

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Hlavní autoři: Chu, Gina Chia-Yi, Zhau, Haiyen E, Wang, Ruoxiang, Rogatko, André, Feng, Xu, Zayzafoon, Majd, Liu, Youhua, Farach-Carson, Mary C, You, Sungyong, Kim, Jayoung, Freeman, Michael R, Chung, Leland W K
Médium: Artigo
Jazyk:Inglês
Vydáno: Bioscientifica Ltd 2014
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3959765/
https://ncbi.nlm.nih.gov/pubmed/24478054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-13-0548
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