RANK- and c-Met-mediated signal network promotes prostate cancer metastatic colonization

Prostate cancer (PCa) metastasis to bone is lethal and there is no adequate animal model for studying the mechanisms underlying the metastatic process. Here, we report that receptor activator of NF-κB ligand (RANKL) expressed by PCa cells consistently induced colonization or metastasis to bone in an...

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Detalhes bibliográficos
Main Authors: Chu, Gina Chia-Yi, Zhau, Haiyen E, Wang, Ruoxiang, Rogatko, André, Feng, Xu, Zayzafoon, Majd, Liu, Youhua, Farach-Carson, Mary C, You, Sungyong, Kim, Jayoung, Freeman, Michael R, Chung, Leland W K
Formato: Artigo
Idioma:Inglês
Publicado em: Bioscientifica Ltd 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3959765/
https://ncbi.nlm.nih.gov/pubmed/24478054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-13-0548
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