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Plasma IL-12 levels are suppressed in vivo by stress and surgery through endogenous release of glucocorticoids and prostaglandins but not catecholamines or opioids

IL-12 is a prominent T(h)1 differentiator and leukocyte activator. Ample studies showed suppression of IL-12 production by numerous stress factors, including prostaglandins, catecholamines, glucocorticoids, and opioids, but did so in vitro and in the context of artificial leukocyte activation, not s...

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Detalhes bibliográficos
Main Authors: Shaashua, Lee, Rosenne, Ella, Neeman, Elad, Sorski, Liat, Sominsky, Luba, Matzner, Pini, Page, Gayle G., Ben-Eliyahu, Shamgar
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3959722/
https://ncbi.nlm.nih.gov/pubmed/24636497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.psyneuen.2013.12.001
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