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Redefining the gut as the motor of critical illness

The gut is hypothesized to play a central role in the progression of sepsis and multiple organ dysfunction syndrome. Critical illness alters gut integrity by increasing epithelial apoptosis and permeability and by decreasing epithelial proliferation and mucus integrity. Additionally, toxic gut-deriv...

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Bibliographic Details
Main Authors: Mittal, Rohit, Coopersmith, Craig M.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3959633/
https://ncbi.nlm.nih.gov/pubmed/24055446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2013.08.004
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