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Real-time evaluation of myosin light chain kinase activation in smooth muscle tissues from a transgenic calmodulin-biosensor mouse

Ca(2+)/calmodulin (CaM)-dependent phosphorylation of myosin regulatory light chain (RLC) by myosin light chain kinase (MLCK) initiates smooth muscle contraction and regulates actomyosin-based cytoskeletal functions in nonmuscle cells. The net extent of RLC phosphorylation is controlled by MLCK activ...

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Detalhes bibliográficos
Main Authors: Isotani, Eiji, Zhi, Gang, Lau, Kim S., Huang, Jian, Mizuno, Yusuke, Persechini, Anthony, Geguchadze, Ramaz, Kamm, Kristine E., Stull, James T.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC395960/
https://ncbi.nlm.nih.gov/pubmed/15071183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308742101
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