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Mechanism-based Treatment in Tuberous Sclerosis Complex

BACKGROUND: Tuberous Sclerosis Complex is a genetic multi-system disorder that affects the brain in almost every patient. It is caused by a mutation in the TSC1 or TSC2 genes, which regulate mTOR, a key player in control of cellular growth and protein synthesis. The most frequent neurologic symptoms...

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Detalhes bibliográficos
Main Authors: Jülich, Kristina, Sahin, Mustafa
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3959246/
https://ncbi.nlm.nih.gov/pubmed/24486221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pediatrneurol.2013.12.002
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